Dyslipidemia: Genetics, lipoprotein lipase and HindIII polymorphism

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Dyslipidemia: Genetics, lipoprotein lipase and HindIII

The direct link between lipid metabolism alterations and the increase of cardiovascular risk are well documented. Dyslipidemias, including isolated high LDL-c or mixed dyslipidemia, such as those seen in diabetes (hypertriglyceridemia, high LDL-c or low HDL-c), correlate with a significant risk of cardiovascular and cerebrovascular disease worldwide. This review analyzes the current knowledge ...

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Dyslipidemia: Genetics, lipoprotein lipase and HindIII

The direct link between lipid metabolism alterations and the increase of cardiovascular risk are well documented. Dyslipidemias, including isolated high LDL-c or mixed dyslipidemia, such as those seen in diabetes (hypertriglyceridemia, high LDL-c or low HDL-c), correlate with a significant risk of cardiovascular and cerebrovascular disease worldwide. This review analyzes the current knowledge ...

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Lipoprotein lipase gene HindIII polymorphism and risk of myocardial infarction in South Indian population.

INTRODUCTION Studies have reported an association between lipoprotein lipase (LPL) gene and myocardial infarction in some populations. Therefore, the present study aimed to investigate the association of the HindIII polymorphism of the (LPL) gene with myocardial infarction and to explore its potential role in susceptibility in a South Indian population. SUBJECTS AND METHODS We included a tota...

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Lipoprotein Lipase HindIII Intronic Polymorphism in a Subset of Iranian Patients with Late-Onset Alzheimer’s Disease

OBJECTIVE Lipid metabolism is involved in the pathogenesis of late-onset Alzheimer's disease (LOAD). Lipoprotein lipase (LPL) is a multifunctional enzyme that plays a major role in lipid metabolism; its abnormal function seems to be related, either directly or indirectly, to the pathogenesis of many diseases such as atherosclerosis, coronary artery disease (CAD) and Alzheimer's disease (AD) . H...

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lipoprotein lipase hindiii intronic polymorphism in a subset of iranian patients with late-onset alzheimer’s disease

objective: lipid metabolism is involved in the pathogenesis of late-onset alzheimer’s disease (load). lipoprotein lipase (lpl) is a multifunctional enzyme that plays a major role in lipid metabolism; its abnormal function seems to be related, either directly or indirectly, to the pathogenesis of many diseases such as atherosclerosis, coronary artery disease (cad) and alzheimer’s disease (ad) . ...

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ژورنال

عنوان ژورنال: F1000Research

سال: 2018

ISSN: 2046-1402

DOI: 10.12688/f1000research.12938.2